depends on the part # and the history of the tuner.

The SF2 or SF3 for fords has canned tunes for most ford vehicles, while the xcal2 or xcal3 do not. The SF2 and SF3 also say xcal2/3 on them, but they also add "strategy flash", that's the important bit if you are looking for something with canned tunes included.

Those canned tunes can be removed if the SF2/3 was used in the past for a custom dyno tune, once a custom tune is loaded the factory canned tunes are usually deleted.

If you are buying local plug it into your truck and try to load a tune before buying it, that will also let you know if it is locked or not.